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OALib Journal期刊

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Lead poisoning due to geophagia: The consumption of miniature pottery  [PDF]
Ashley Phipps, Heather Fels, Mackenzie S. Burns, Shawn L. Gerstenberger
Open Journal of Pediatrics (OJPed) , 2012, DOI: 10.4236/ojped.2012.21010
Abstract: Geophagia (the pica of pottery, clay, earth, or dirt) is practiced before and during pregnancy in several countries, including Mexico, Turkey, Australia, and some African countries, and has been linked with cultural fertility beliefs and the satisfaction of cravings. Unfortunately, consumption of contaminated pottery can represent a source of lead exposure. Concerns regarding ingested pottery are two-fold; first, that people consuming these pots might be exposed to high concentrations of lead, and, second, that ingestion of these pots by pregnant women could result in elevated in utero lead exposure for the fetus. Very few published articles exist on this topic. In an effort to investigate “pot eating”, this study aims to summarize published case studies on lead poisonings resulting from consumption of contaminated pottery. Additionally, several pottery items that are sold for the purpose of consumption were located and analyzed. This paper investigates the risk that “pot eating” poses by reviewing the literature, examining case studies, and analyzing the availability and lead concentration of edible pottery. Preliminary research indicates that although it is not common, “pot eating” can represent a high-risk lead exposure for pregnant women and their fetuses.
The Effects of Soil pH on Setaria viridis and Abutilon theophrasti Seedling Growth and Tissue Nutrients
Jack Dekker,Heather MacKenzie,Kevin Chandler,Jack Dekker
Agricultural Journal , 2013,
Abstract: Weeds vary in their response to soil pH in how they become established, grow and thrive. Knowledge of how a weed species responds to soil pH could help in evaluating their competitive ability against crops under different soil conditions and provide valuable insights into their biology and adaptation in agroecosystems. Studies were conducted to determine the effect of three soil pHs (4.3, 5.3, 6.9) on the seedling growth of Setaria viridis and Abutilon theophrasti in terms of seedling shoot biomass accumulation and tissue nutrient content. The effect of several postemergence-applied herbicides (bentazon, cyanazine and 2,4-D) on established seedlings of those species was also investigated. Untreated Setaria viridis, as well as untreated and treated (bentazon, cyanazine and 2,4-D) Abutilon theophrasti, seedlings accumulated less biomass as the soil pH decreased from neutral to acidic reaction. In both species this reduction in growth was associated with interference of uptake and incorporation of calcium, magnesium and phosphorus, as well as toxicity caused by excessive amounts of aluminum, manganese and zinc in seedling tissue. These nutrient imbalances also led to enhanced injury of Abutilon theophrasti with bentazon, cyanazine and 2,4-D.
Disruption and Disposition in Lifelong Learning
Anne Edwards,Lin MacKenzie,Stewart Ranson,Heather Rutledge
Outlines : Critical Practice Studies , 2002,
Abstract: UK government policies for social inclusion through engaging with the learning society aim at repositioning people as capable participants in their social worlds. These policies at first sight appear to be aimed at a sophisticated restructuring of social contexts as well as at an enhancing of individual learning. However there is a degree of conceptual confusion within these policies. In this paper we explore some of the tensions evident in a study of a family learning centre in an English city. In the exploration we examine the extent to which the tools offered by sociocultural and activity theory (SAT) can assist in resolving that conceptual confusion and how SAT itself might need to develop in order to analyse complex and sustained forms of intervention.
Measuring the relationship between interruptions, multitasking and prescribing errors in an emergency department: a study protocol
Dana Strumpman,Heather E Douglas,Johanna I Westbrook,John Mackenzie,Magdalena Z Raban,Scott R Walter
- , 2015, DOI: 10.1136/bmjopen-2015-009076
Abstract: Introduction Interruptions and multitasking are frequent in clinical settings, and have been shown in the cognitive psychology literature to affect performance, increasing the risk of error. However, comparatively less is known about their impact on errors in clinical work. This study will assess the relationship between prescribing errors, interruptions and multitasking in an emergency department (ED) using direct observations and chart review. Methods and analysis The study will be conducted in an ED of a 440-bed teaching hospital in Sydney, Australia. Doctors will be shadowed at proximity by observers for 2?h time intervals while they are working on day shift (between 0800 and 1800). Time stamped data on tasks, interruptions and multitasking will be recorded on a handheld computer using the validated Work Observation Method by Activity Timing (WOMBAT) tool. The prompts leading to interruptions and multitasking will also be recorded. When doctors prescribe medication, type of chart and chart sections written on, along with the patient's medical record number (MRN) will be recorded. A clinical pharmacist will access patient records and assess the medication orders for prescribing errors. The prescribing error rate will be calculated per prescribing task and is defined as the number of errors divided by the number of medication orders written during the prescribing task. The association between prescribing error rates, and rates of prompts, interruptions and multitasking will be assessed using statistical modelling. Ethics and dissemination Ethics approval has been obtained from the hospital research ethics committee. Eligible doctors will be provided with written information sheets and written consent will be obtained if they agree to participate. Doctor details and MRNs will be kept separate from the data on prescribing errors, and will not appear in the final data set for analysis. Study results will be disseminated in publications and feedback to the ED
The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network
Cassandra M. Leech,Haibo Liu,Heather E. Arsenault,Jennifer A. Benanti,Jianhong Ou,Lihua Julie Zhu,Mackenzie J. Flynn
- , 2020, DOI: 10.1371/journal.pgen.1008600
Abstract: Upon exposure to environmental stressors, cells transiently arrest the cell cycle while they adapt and restore homeostasis. A challenge for all cells is to distinguish between stress signals and coordinate the appropriate adaptive response with cell cycle arrest. Here we investigate the role of the phosphatase calcineurin (CN) in the stress response and demonstrate that CN activates the Hog1/p38 pathway in both yeast and human cells. In yeast, the MAPK Hog1 is transiently activated in response to several well-studied osmostressors. We show that when a stressor simultaneously activates CN and Hog1, CN disrupts Hog1-stimulated negative feedback to prolong Hog1 activation and the period of cell cycle arrest. Regulation of Hog1 by CN also contributes to inactivation of multiple cell cycle-regulatory transcription factors (TFs) and the decreased expression of cell cycle-regulated genes. CN-dependent downregulation of G1/S genes is dependent upon Hog1 activation, whereas CN inactivates G2/M TFs through a combination of Hog1-dependent and -independent mechanisms. These findings demonstrate that CN and Hog1 act in a coordinated manner to inhibit multiple nodes of the cell cycle-regulatory network. Our results suggest that crosstalk between CN and stress-activated MAPKs helps cells tailor their adaptive responses to specific stressors
A Note on the Validity of the Shannon Formulation for Fitts’ Index of Difficulty  [PDF]
Ian Scott MacKenzie
Open Journal of Applied Sciences (OJAppS) , 2013, DOI: 10.4236/ojapps.2013.36046
Abstract:

The three most common variations of Fitts’ index of difficulty are the Fitts formulation, the Welford formulation, and the Shannon formulation. A recent paper by Hoffmann [1] critiqued the three and concluded that the Fitts and Welford formulations are valid and that the Shannon formulation is invalid. In this paper, we challenge Hoffmann’s position regarding the Shannon formulation. It is argued that the issue of validity vs. invalidity is ill-conceived, given that Fitts’ law is a “model by analogy” with no basis in human motor control. The relevant questions are of utility: Does a model work? How well? Is it useful? Where alternative formulations exist, they may be critiqued and compared for strengths and weaknesses, but validity is an irrelevant construct. In a reanalysis of data from Fitts’ law experiments, models built using the Shannon formulation are (re)affirmed to be as good as, and generally better than, those built using the Fitts or Welford formulation.

HIV Prevention in Papua New Guinea: Is It Working or Not?  [PDF]
Heather Worth
World Journal of AIDS (WJA) , 2012, DOI: 10.4236/wja.2012.23016
Abstract: Introduction: There is a global call for structural approaches to HIV that go beyond awareness and HIV testing to approach prevention work via the social and economic drivers of the epidemic. Papua New Guinea is the epicentre of the HIV epidemic in the Pacific, with an adult prevalence rate of 0.9%. Since 2004, there has been a concerted response to HIV, with vastly increased rates of HIV testing and roll-out of antiretroviral therapy, and considerable funding for HIV prevention. Objectives: While incidence is slowing there are still a considerable number of new infections each year and many commentators are worried that HIV prevention is not working in that country. This article aims to critically examine HIV prevention programs in Papua New Guinea to show whether HIV prevention is effectiveness in reaching those most vulnerable to infection. Methods: Using data from HIV prevention programs and behavioural surveys this article will assess how HIV prevention has been carried out and the effectiveness of those programs. Results: There is little evidence to indicate that HIV prevention in Papua New Guinea, particularly among those most at risk of HIV has been successful. Conclusion: there is a dearth of HIV prevention interventions in Papua New Guinea that go beyond awareness-raising to deal with the structural drivers of the epidemic.
An Experimental Study of the Reduplication of Gradable Adjectives in Mandarin Chinese  [PDF]
Heather Pan
Open Journal of Social Sciences (JSS) , 2020, DOI: 10.4236/jss.2020.88037
Abstract:
Compared to English, Mandarin Chinese has a rich inventory of reduplicated forms of adjectives. It has been argued that reduplicated forms of gradable adjectives convey an additional inference that the speaker has the relevant direct perceptual experience (Tang, 1988; Zhu, 2003; Liu, 2013). This article invesigates whether the reduplicated form has this additional perceptual inference for native speakers by experimental studies. Our experiment results show that the reduplicated form of scalable adjectives does not require the perceptual inference compared to its base form, contra the previous studies.
Retro-orbital and disseminated B-cell lymphoma in a yellow-collared macaw (Primolius auricollis)
Chantale Pinard,Dale A. Smith,Emily Brouwer,Heather Chalmers,Hugues Beaufrère,Josepha DeLay,Kim Le,R. Darren Wood,S. Karlyn Bland,Sarah Wills,Shawn MacKenzie
- , 2017,
Abstract:
Imperialism, Human Rights and War: Review of Jean Bricmont’s 'Humanitarian Imperialism; Using Human Rights to Sell War'
Sarah MacKenzie
Journal of Critical Globalisation Studies (JCGS) , 2010,
Abstract:
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